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New Zealand Colostrum’s Immune
Factors
Immune Factors in bovine colostrum have been shown to help the body inhibit
the binding of pathogenic invaders to the gastrointestinal (GI) tract. Each
factor plays a specific role in our body’s defense against these attackers. In
addition, colostrum contains over 20 antibodies to specific pathogens
including E coli, salmonella, rotavirus, candida, streptococcus,
staphylococcus, H pylori, and cryptosporidia.
In addition to immunoglobulins, medical studies show that PRP in bovine
colostrum supports an underactive immune system. PRP also helps balance an
overactive immune system present in autoimmune conditions.
Assist the internal regulation of the brain's "feel-good" chemicals, supporting alertness and better concentration.
Other Beneficial Components
Vitamins and Minerals are nutrients that
are essential for normal metabolism, growth and development. They act as
coenzymes, enabling metabolic processes to take place throughout the body.
Vitamins and minerals are indispensable for the maintenance of health.
Amino acids are the building blocks of proteins. They are required for growth
and development. Amino acids are divided into essential (not produced by the
body) and nonessential (can be produced by the body).
Known Components in Colostrum.
Vitamins and Other Nutrients
Vitamin B6 – Produces serotonin, utilization of amino acids
Vitamin B12 – Normal development of red blood cells
Vitamin E – Antioxidant, supports wound repair and immune
function
Vitamin A (from carotene) – Resistance to pathogenic
invasion, maintains cell integrity
Vitamin C – Antioxidant, immune system support
Thiamin (Vitamin B1) – Metabolism of carbohydrates, energy
Folic Acid – Cell replication and tissue growth
Pantothenic Acid – Metabolism of fats, carbohydrates and
protein
Riboflavin (Vitamin B2) – Energy production, tissue repair,
healthy eyes
Beta-carotene - Antioxidant
Glycoconjugates – Carbohydrates that link to lipids and
proteins
Glycogen – Converts into glucose when needed by tissues
Retinoic Acid – Metabolite of Vitamin A, used in treatment of
acne
Minerals
Calcium – Maintains strong, healthy bones, activates enzymes
Chromium – Glucose metabolism disorders, body fat reduction
Iron – Oxygen transport and storage, energy, immune support
Magnesium – Muscle relaxation, assists with normal brain
function
Phosphorus – Strengthens bones and teeth
Potassium – helps maintain normal blood pressure, maintains
fluid balance in cells
Sodium – Cell membrane integrity, plays important role in
nerve function
Zinc – Synthesis of DNA and RNA, activates Vitamin A
Essential Amino Acids
Isoleucine – Assists in muscle development & repair, helps
regulate blood sugar
Leucine – Involved in muscle repair, wound healing and
hormone production
Histidine – Involved in growth and tissue repair
Methionine – Antioxidant, collagen synthesis, helps support
healthy cardiovascular function
Lysine – Aids in calcium absorption, helps regulate antibody
and enzyme production
Threonine – Stimulates antibody production
Phenylalanine – Assists neurotransmitter function, increases
“feel good” chemicals in brain
Valine – Regulates energy, aids growth and repair of muscle
tissue
Tryptophan – Stimulates niacin production, precursor for
serotonin
Nonessential Amino Acids
Arginine – Stimulates GH, immune function, promotes wound
repair and muscle growth
Cystine – An antioxidant involved in collagen synthesis
Glutanic Acid – Helps transport potassium to the brain,
implicated in neurological conditions
Alanine – Involved in glucose metabolism
Tyrosine – Regulate mood, may improve memory, appetite
suppressant
Glycine – Helps decrease muscle wasting, aids in glycogen
storage
Proline – Aids in wound repair and collagen synthesis
Aspartic Acid – Helps synthesis of DNA, RNA, Ig and
antibodies, involved in energy metabolism
Serine – Involved in fat metabolism and muscle growth, noted
moisturizer
Additional Factors Found in Colostrum
Beta 2- microglobulin – Components of many cell membranes
including leukocytes
Enzymes – Induce chemical changes in the body
Haemopexin – Iron-binding protein
Haptoglobulin – Glycoproteins that aid the recycling of iron
Lactoperoxidase – An antioxidant
Orotic Acid – Precursor to certain nucleotides
Peroxidase – Transfers oxygen to tissues, helps prevent free
radical damage
Xanthine Oxidase Enzyme – Enzyme involved in conversion of
hypoxanthine to xanthine
Lactobacillus Acidophilus, Bifidobacterium, Lactobacillus Bifidus
– Help restore a supportive bacterial environment in the body

" New Zealand is The World Leader in Grazing Production Systems ”
“ Some US producers are hanging their hopes on a modified New Zealand system- to help them become efficient enough to stay in business. “
“ Pasture-based, seasonal milk-production systems used in New Zealand are being modified for the Missouri Ozarks.”
“ Having managed my own dairy operation since 1936, I was interested in the modus operandi of dairy farmers in New Zealand”
One of the reasons for this high regard is that New Zealand dairies are held to some of the most stringent standards in the world. In New Zealand, the Dairy and Plant Products Group (a division of the Ministry of Agriculture and Forestry-MAF) provides assurance to consumers, both domestic and international, that New Zealand’s dairy products are safe and true to label. And, the government mandates that all dairy products (colostrum included) must be free of antibiotics, chemical residues and hormones (rbST is illegal in New Zealand).
Key differences between Colostrum Produced in the U.S. and New Zealand :
New Zealand United States Feeding practices (1) Free-grazing pastures Confined feed lots Climate (2) Mild temperate temperatures Subject to extreme temperatures Regulations/ GMPs (3) Controlled by MAF None currently mandated Certification (4) Ministry of Agriculture and Forestry None required Calf birthing (5) Once per year (July-September), or according to natural cycle at organic dairies Calving intervals of 2 months Storage (6) Refrigerated vats Frozen Pasteurization (7) Flash Pasteurized (161°F for 15 sec.) Mostly High Heat Pasteurized Antibiotic use (8) Illegal in NZ Practiced on most dairy farms Hormones (9) Illegal in NZ Currently allowed Penalties for contamination infractions (10) Fines up to $100,000 possible Considered misdemeanor / no fines
Grazing practices, the treatment of cattle, collection and storage methods, and processing all affect the quality of colostrum.- When choosing a Colostrum Supplement, It is important to keep These Points in mind.
(1) Pasture fed cattle are exposed to a wide variety of soil-based pathogens, which means they will naturally develop more antibodies. Healthy green grass also provides beneficial enzymes, some of which end up in the Colostrum, aiding in its assimilation. Intensively managed, year-round pastures in New Zealand furnish nearly 100% of herd feed requirements, so the cows need little or no supplemental grain. At organic dairies on New Zealand's north island which supply exclusive organic Source Colostrum, cattle are actually 100% pasture-fed, providing the optimal environment for effective colostrum.
In New Zealand-style grazing systems, the animals are rotated frequently to fresh, small pastures and produce more milk per acre. A 1993 survey determined that greater than 40% of United States dairy heifer calves had serum immunoglobulin G (IgG) concentrations of less than 10 mg/ml. The Journal of Dairy Sciences reports, “U.S. society will soon demand that agriculture back off, at least to some extent, from confinement and pay greater attention to agricultural animal comfort and happiness.”
(2) In New Zealand, dairy farmer Brian Thompson states,” We have high-quality ryegrass and white clover pasture virtually year round. Our climate is mild with only four or five frosts and no hard freezes in winter." In the US, extreme cold temperatures or windchills will increase the cow's energy needs. If this energy is not fed in the diet, the cow will take nutrients from its body to meet energy demands. Likewise, extremely hot weather often results in low colostrum production.
(3) In New Zealand, the MAF Dairy and Plant Products Group convenes twice a year to review the MAF standards relating to colostrum. Colostrum production, storage and transportation must be in accordance with a product safety program. While in the U.S., the Public Health Service has no legal jurisdiction in the enforcement of milk or milk product sanitation standards; only now is the Food and Drug Administration (FDA) considering whether to institute rulemaking to develop current good manufacturing practice (CGMP) regulations for dietary supplements, including colostrum.
(4) In New Zealand, all dairy farms and milk production facilities must be certified by the MAF, while in the US, no such certification exists. Domestically, states and communities are encouraged to implement the Grade "A" Pasteurized Milk Ordinance, but it is not a requirement. Also, the “Grade A” standard was not developed with colostrum in mind, unlike the New Zealand regulations, and has no guidelines about how colostrum should be harvested, transported, processed and stored for maximum potency and safety.
New Zealand Colostrum products meet all the stringent standards for quality and safety set out by New Zealand's MAF(Ministry of Agriculture and Forestry) and NZFSA (New Zealand Food Safety Authority).
(5) New Zealand farmers begin their six- to eight-week breeding season in September. The cows calve in July and August- winter in the southern hemisphere-and are weaned in mid-May.. (About 95% of the country's dairy herds follow this schedule.) The exception is New Zealand's organic dairies, which breed cattle year-round according the their natural health cycle.
Most US dairy operators strive for a calving interval of 2 months (this goal is rarely achieved)The concern from activists is that nearly continuously pregnant cows are constantly burdened with carrying large quantities of milk. And, the induction of ovulation has been associated with side effects such as abnormal estrous behavior, reduced fertility, cystic follicles and corpora lutea, and chronic vaginal prolapse. Some US producers are hanging their hopes on a modified New Zealand breeding system to help them become efficient enough to stay in business
(6) Colostrum in New Zealand is collected fresh in sterile, refrigerated vats. This process helps maintain the bioactivity of colostrum’s fragile components while protecting it from bacterial contamination. The colostrum is then immediately processed to protect vital components. Freezing colostrum is an acceptable method for storing excess colostrum on dairy farms, however the method in which it is stored and subsequently thawed, needs to be very exacting if the fragile active components are to be safeguarded.Frozen colostrum needs to be stored in small freezer bags (unlikely with large amounts of colostrum for mass production). Because the antibodies and immunoglobulins in colostrum are proteins, careful thawing, at low temperatures is essential to maintain biological activity. Metafoods New Zealand Colostrum is either spray-dried or freeze-dried with state-of-the-art technologies to ensure our colostrum's potency.
(7) Pasteurization is required to eliminate dangerous bacteria that can be found in all milk products (including colostrum). In ordinary high temperature short time (HTST, 72° C / 15 sec) also known as “flash pasteurization,” only 0.5 -10 % of Ig activity is lost. However, high temperatures (167°F and over) destroy colostrum’s overall effectiveness, as illustrated in the chart below. To maintain the integrity of the product, New Zealand only uses low heat processing and flash pasteurization, rather than the high heat required by US law for full fat dairy products.
Thermal Denaturation of Immunoglobulins During Processing
Temperature (ºC) D-Value (seconds)
69 8504
72 1387
77 285
81 152
D-value = time to inactivate 90% of the IgG
(8) The use of antibiotics is illegal in the New Zealand dairy industry. The MAF requires a screening test for antibiotic residues, while in the US, antibiotic use is widely practiced on dairy farms. Most US dairy farms store antibiotics on the premises to treat cows that are about to give birth.The Dairy Science and Technology division of the University of Guelph reports, “the presence of antibiotic residues in milk products is very problematic for at least three reasons;
· In the production of fermented milks, antibiotic residues can slow or destroy the growth of the fermentation bacteria.
· From a human health point of view, some people are allergic to specific antibiotics, and their presence in food consumed can have severe consequences.
· Frequent exposure to low level antibiotics can cause microorganisms to become resistant to them, through mutation, so that they are ineffective when needed to fight a human infection.
For these reasons, it is extremely important that milk from cows being treated with antibiotics is withheld from the milk supply.”
We’ll go even further. While certain antibiotics can be extremely helpful in combating short-term bacterial infection, their long-term ingestion, even in small amounts can actually weaken human immune systems. Also, antibiotics destroy beneficial bacteria or probiotics in the human digestive tract which are critically important for overall digestive health, including the assimilation of food and micronutrients such as vitamins, and the bioactive factors in colostrum.
(9) Dairy management systems in New Zealand prohibit the use of hormones. In the US, hormones like rbST (recombinant bovine somatotropin) are used to stimulate growth and milk production. Research shows that higher producing cows are more likely to have lower concentrations of IgG in their colostrum at calving. The sale of milk from cows treated with recombinant bovine growth hormone (rbGH) is also approved in the US. Recent studies find that milk quality may actually be degraded somewhat as a result of the increased incidence of mastitis associated with the use of rbGH/rbST. In several countries, milk quality is measured by somatic cell counts (SCC).SCC are significantly elevated in the milk of rbGH/rbST-treated cows. Milk with a high SCC tends to spoil faster than milk with lower SCC. Also, a decline in nutritional quality and protein content has been observed in the early stages of supplementation with rbGH/rbST.
Finally, no scientists and medical researchers are yet certain of the effects on humans of minute residues of bovine hormones in dairy products. Since hormones naturally occur in our bodies in infinitesimal quantities, and still create powerful effects, it seems to make sense (at least to us) to be cautious about ingesting any hormones (or residues of hormones) which are not prescribed by a health care professional.
(10) In New Zealand, farmers may be fined up to $100,000 for infractions against regulations, including the presence of hormones, antibiotics or pesticides. According to the US Grade A Pasteurized Milk Ordinance, “No penalty is imposed on the producer… or distributor upon the first violation of any of the sanitation requirements…” Additional infractions are considered misdemeanors and no fines are imposed.
- So, where do you want your colostrum to come from?
References :
- Miller, M. 2002, Colostrum in Newborn Calves
- Rollin, B. E. 1990. Animal welfare, animal rights, and agriculture. Journal of Animal Science 68:3456-3461.
- Federal Register: 1997 (Volume 62, Number 25) Proposed Rules
- U.S. Department of Health and Human Services Public Health Service Food and Drug Administration Grade A- Pasteurized Milk Ordinance Revised 1999
- Manning, E. Dairying New Zealand Style July 2001
- Erb, R. E. 1977. Hormonal control of mammogenesis and onset of lactation in cows —- A review. Journal of Dairy Science 60:155-169.
- Sawyer, G. J., W. J. Fulkerson, G. B. Martin, and C. Gow. 1986. Artificial induction of lactation in cattle: Initiation- of lactation and estrogen progesterone concentrations in milk. Journal of Dairy Science 69:1536-1544.
- Pritchett, L.C., et al. Management and production factors influencing immunoglobulin G1 concentration in- colostrum from Holstein cows. 1991, J Dairy Sci, 74:2336.
- USDA, APHIS, Veterinary Services. Transfer of maternal immunity to calves. Highlights of the National Dairy- - Heifer Evaluation Program. 1993 Bulletin No. N118.0293, USDA, Animal Plant Health Inspection Service, Fort
- Collins, CO.
- Li-Chan et al. , 1995
- TB Mepham, "Public health implications of bST use in dairying: discussion paper, "Joumal of the Royal Society- of Medicine 85: 736-739, 1992.
- J.C. Juskevich and C. G. Guyer, "Bovine Growth Hormone: Human Food Safety Evaluation,"- Science 249: 875-884, 1990.
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